A scientist has found a way to prevent inflammation and bone loss surrounding the teeth by blocking a natural signaling pathway of the enzyme GSK3b, which plays an important role in directing the immune response.
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Bacteria on marine sponges can develop capacity to move and inhibit biofilm formation
A new study shows that when enough bacteria get together in one place, they can make a collective decision to grow an appendage and swim away. This type of behavior has been seen for the first time in marine sponges, and could lead to an understanding of how to break up harmful bacterial biofilms, such as plaque on teeth or those found on internal medical devices like artificial heart valves.
Coconut oil could combat tooth decay
Digested coconut oil is able to attack the bacteria that cause tooth decay. It is a natural antibiotic that could be incorporated into commercial dental care products, say scientists.
Mom’s emotional health during child’s early years linked to teen’s oral health
A mother’s emotional health and education level during her child’s earliest years influence oral health at age 14, according to a new study.
Evidence that new biomimetic controlled-release capsules may help in gum disease
Scientists are trying to open a new front in the battle against gum disease, the leading cause of tooth loss in adults and sometimes termed the most serious oral health problem of the 21st century. They have developed a new treatment approach.
Poor oral health can mean missed school, lower grades
Poor oral health, dental disease, and tooth pain can put kids at a serious disadvantage in school, upping the risk of low grades and more absences.
Stem cell therapy could offer new hope for defects and injuries to head, mouth
In the first human study of its kind, researchers found that using stem cells to re-grow craniofacial tissues—mainly bone—proved quicker, more effective and less invasive than traditional bone regeneration treatments.
One step closer to growing a tooth
To build a tooth, a detailed recipe to instruct cells to differentiate towards proper lineages and form dental cells is needed. Researchers have now found a marker for dental stem cells. They showed that the transcription factor Sox2 is specifically expressed in stem cells of the mouse front tooth.
Short-term intestinal parasite infection triggers specific cytokines that can prevent the development of type 1 diabetes
Short-term infection with intestinal worms may provide long-term protection against type I diabetes (TID), suggests a new study. The incidence of TID is relatively low in developing countries. One explanation for this phenomenon is the prevalence of chronic intestinal worm infections, which dampen the self-aggressive T cells that cause diabetes and other autoimmune diseases.
Discovery of epigenetic links in cell-fate decisions of adult stem cells paves way for new osteoporosis treatments
The ability to control whether certain stem cells ultimately become bone cells holds great promise for regenerative medicine and potential therapies aimed at treating metabolic bone diseases, especially osteoporosis. Now, scientists have made a significant breakthrough in that direction. The scientists have discovered two key epigenetic regulating genes that govern the cell-fate determination of human bone marrow stem cells.